Is Mixing Cymbalta (Duloxetine) and Alcohol Safe?

Cymbalta is a brand name for duloxetine, a serotonin-norepinephrine reuptake prevention (SNRI) that is suggested to deal with a range of problems consisting of stress and anxiety and also clinical depression.

It is also utilized to treat fibromyalgia, nerve discomfort, and chronic pain. It may also be recommended off-label to deal with chronic fatigue syndrome, lower pain in the back, and also stress-related urinary incontinence.

This medicine can have a variety of effects on your body and also it may create undesirable negative effects if you blend it with alcohol or other compounds. If you are currently taking Cymbalta, it is very important to be familiar with the prospective side effects, communications, and risks of blending this medicine with alcohol.

Can You Consume Alcohol When Taking Cymbalta?

A worry about drinking when you are taking Cymbalta is the potential threat for liver damage. This is generally more of a problem for people that are problem drinkers or who have a history of heavy or persistent alcohol abuse.

While increased psychological problems is frequently an issue when mixing medicine with alcohol, the maker mentioned that Cymbalta did not enhance the problems of psychological as well as motor skills caused by alcohol.

That does not indicate that there are no threats. Alcohol might contribute to a boost in mood-related signs or may even disrupt your treatment.

If you are taking Cymbalta and wish to know if it is risk-free to have a beverage or more, speak to your doctor. Since they recognize your circumstance as well as history, they can make suggestions based upon your requirements as well as health and wellness.

They can also educate you about several of the prospective dangers of mixing Cymbalta and also alcohol. These dangers are listed here.

Threat of Liver Damage

Both alcohol and also Cymbalta can bring about liver damages. Taking these 2 compounds with each other can enhance this threat.

Your liver breaks down the substances you take in and also eliminates toxic substances from your body. Because alcohol contains a variety of toxic substances, persistent use can eventually exhaust your liver and also result in liver damages. Cymbalta has likewise been linked to liver damages.

According to the FDA’s suggesting details for Cymbalta, the medicine is not suggested for people who routinely take in alcohol. People who have a history of liver issues or liver damage will certainly have lowered metabolic process of this medication.

Some indications of prospective liver damages include:

Stomach discomfort

Dark-colored urine


Scratchy skin

Nausea or vomiting as well as vomiting

Yellowing of the skin or eyes

If you experience any one of these signs and symptoms while taking Cymbalta, you should call your doctor immediately.

Worsening of Adverse Effects

Drug communications can in some cases increase the undesirable negative effects of each material. The FDA records that when Cymbalta and also alcohol are taken to ensure that their peak impacts correspond, using Cymbalta did not aggravate the motor or psychological problems triggered by alcohol. Nonetheless, incorporating both materials might add to a worsening of opposite effects.

Typical adverse effects of Cymbalta include:


Reduced appetite







You might find that you experience such signs much more really if you consume alcohol while you are taking Cymbalta.

Boosted Signs And Symptoms of Depression as well as Stress and anxiety

While Cymbalta is commonly recommended to deal with clinical depression, it can destabilize mood in some circumstances. When integrated with alcohol, it might also decrease the efficiency of the medicine. This can bring about a worsening of signs and symptoms of clinical depression as well as anxiety.

Some state of mind signs that might raise in severity because of this consist of:

Changes in mood

Adjustments in sleep

Sensations of stress and anxiety or panic


Ideas of suicide

While it might appear like alcohol can result in improvements in state of mind in the short-term, it likely will contribute to an increase in state of mind symptoms such as clinical depression and also anxiousness over the long term.

Kids, teens, and young adults may also experience an increase in self-destructive ideas as well as behaviors, especially when they first start taking Cymbalta. Alcohol might increase this danger if it is taken in while you are taking your medicine.

Taking Cymbalta for Alcohol Withdrawal

If you are trying to quit consuming alcohol or if you have just recently stopped, talk with your physician regarding whether Cymbalta might be a choice. There is some research study recommending that duloxetine may be useful in lessening anxiety-like behaviors as well as alcohol intake, which may make it beneficial as a treatment during alcohol withdrawal.

One study found that treatment with a reduced dose of duloxetine significantly lowered alcohol use. The research study also located that this decrease in drinking was likewise accompanied by a decrease in anxiety-related habits.

If you are taking out from alcohol, however, you should never take Cymbalta or other medications including duloxetine without first consulting your doctor. Your doctor can examine your wellness and guide you through the withdrawal process based on your unique demands and situation.

Before You Mix Cymbalta as well as Alcohol

If you are thinking about attempting Cymbalta for clinical depression, stress and anxiety, or other disease, review your options with your doctor. Make sure to ask whether it is alright to consume or take other medicines while you are taking Cymbalta.

You need to likewise be sure to tell your medical professional regarding any other drugs, supplements, or substances that you are taking. Various other compounds that can engage with Cymbalta include various other antidepressants, blood thinners, and also St. John’s wort.

Your doctor might advise that you prevent alcohol throughout your initial therapy or recommend that you take in only small amounts of alcohol while taking the drug. Or they may advise that you prevent it entirely based upon your physical as well as mental health history.

Make sure that you do not stop taking your antidepressant or alter your dose without very first speaking to your doctor. Your medical professional can aid you securely quit taking your medicine by progressively lowering your dose.

By Master James

Master James, a versatile wordsmith, possesses an unparalleled ability to delve into the depths of the General Niche, exploring a myriad of topics with finesse. His literary prowess extends across the vast tapestry of the USA, crafting engaging narratives that captivate readers from coast to coast. With a keen eye for detail and a passion for knowledge, Master James weaves together insightful perspectives on a broad spectrum of subjects, creating a literary landscape that mirrors the rich diversity of the American experience.

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